| Efecto del calcio, la glucosa y la trifluoperazina sobre la carboxilmetilacion de proteinas en islotes pancreaticos de rata. |
| Mena, P; Barriga, C; Campillo, J E; |
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| Departamento de Fisiologia, Universidad de Extremadura, Badajoz, Espana. |
| In the isolated pancreatic islets incubated in vitro, carboxylmethylation increases following stimulation with 20 mM glucose. This increase is dependent on extracellular calcium concentration and is suppressed in the presence of trifluoperazine, a calmodulin inhibitor. In conclusion, the increase in carboxylmethylation induced by 20 mM glucose seems to be a calcium-dependent process and it is probably mediated by calmodulin. |
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